Britton Chance (1913-2010) was a biochemist and biophysicist as well as a pioneer in the field of biomedical optics. Chance received his Ph.D. in Physical Chemistry from the University of Pennsylvania in 1940 and his Ph.D. in Biology and Physiology from Cambridge University in 1942. Over the course of his nearly eight decade career, Chance was dedicated to the application and transfer of basic scientific research and technology to clinical medicine. The Britton Chance Papers contain correspondence, research notes, experimental data, publication materials, and photographs stemming from Chance's life as a biochemist, biophysicist, and yachtsman. The collection is broken up into fifteen series that document every aspect of his scientific work.

The physicist W.F.G. Swann was a pioneer in high energy physics and the study of cosmic rays. Climbing the academic ranks from the University of Sheffield to the Universities of Minnesota, Chicago, and Yale, Swann was selected as the first director of the Bartol Research Foundation of the Franklin Institute in 1927, and remained there until his retirement in 1959. An able administrator and excellent mentor, he was best known for his popular work on the new physics, The Architecture of the Universe (1934) and for his research on cosmic rays. Avocationally, he was an accomplished cellist and in addition to performing, he helped organize and support the Swarthmore Symphony Orchestra and other local groups. He died at his home in Swarthmore in 1962. The Swann Papers consist of 41 linear feet of correspondence, class notes, lectures, and photographs documenting Swann's career at the Bartol Research Foundation from 1927 until the end of his life. The collection is wide ranging, touching on atmospheric electricity, particle acceleration, atomic bomb defense, atomic energy, electrets, electrodynamics, magnetism, music, quantum theory, radiation, relativity and Einstein, science and civilization, stratospheric flights (by balloon and airplane), thermodynamics, psychic science, and wave mechanics. It is particularly rich for study of the history of cosmic ray research and the Bartol Institute, and for study of the popularization of modern physical sciences.

A biochemist at Columbia University, Erwin Chargaff discovered the base-pairing regularities or "complementarity relationships" of nucleic acids that provided one of the key steps in developing a structural model for DNA. During his long career, Chargaff is credited with conclusively falsifying the tetranucleotide hypothesis; demonstrating the existence of a large number of DNA species; and creating the first descriptions of hypochromicity, hyperchromicity, and the denaturation of a DNA. In addition, Chargaff conducted important research on blood coagulation, lipids and lipoproteins, the metabolism of amino acids and inositol, and the biosynthesis of phosphotransferases. He retired to emeritus status in 1974 and remained active in research almost to the time of his death in June 2002. The Chargaff Papers are organized into ten series: I. Correspondence, 1931-1992; Ia. Correspondence, 1949-2002; IIa. Grants, 1930-1982; IIb. Subject Files, 1940-1984; IIc. Subject Files, 1946-2002; III. Works by Chargaff, 1929-1989; IIIa. Works by Chargaff, 1923-2002; IIIb. Reprints, 1977-1999; IV. Works by Others, 1936-1985; IVa. Works by Others, 1976-2002; V. Research Notes and Notebooks, 1929-1951 ; VI. Photographs, 1935-1977; VIa. Photographs, 1928-2002; VII. Audiovisual Materials; VIII. Awards and Certificates, 1958-2001; IX. Lecture Notes, 1942-1985; X. Personal Papers, [1880]-1985.

One of the most influential statisticians of the twentieth century, John Wilder Tukey (1915-2000) played a key role in both the development and study of statistics. Upon receiving his Ph.D. in mathematics in 1939 from Brown University, he joined the faculty at Princeton; in 1945, he also began work at Bell Laboratories. Equally committed to both Princeton and Bell Labs, Tukey chose to work concurrently at both institutions. He was also a consultant for many companies, such as Merck and Company, Xerox Corporation, and the Educational Testing Service, and was a frequent advisor to the government for such programs as the US Census. From 1960 to 1980 he led the statistical component of NBC's election night projections. Among other projects Tukey analyzed Alfred Kinsey's research and examined data on ozone depletion. Tukey made many important contributions to the field of statistics, such as work in time series analysis, exploratory data analysis, and multiple comparisons. Through his work, Tukey developed statistical applications including the Box-and-Whisker Plot, the Stem-and-Leaf Diagram, Cooley-Tukey Fast Fourier Transforms, Tukey's Paired Comparisons and citation and permutated indices. Tukey's influence extends beyond statistics to everyday language: he was the first to use the word "software" in print and coined words such as "bit" and "linear programming." A prolific writer, John W. Tukey penned more than 500 technical papers and reports and published, among numerous other works. His collected papers amount to eight volumes of work. The Tukey Papers provides a comprehensive perspective into Tukey's professional activities from his days as a graduate student until his death in 2000. Among the material is his correspondence and his published and unpublished works. There is abundant material from Tukey's long careers at Bell Laboratories and Princeton University, including extensive lecture notes and syllabi. Also included are copious materials relating to his professional activities with such agencies as the National Research Council, the Army Records Office, Xerox PARC, Merck and Company, the President's Science Advisory Committee, and the National Academy of Sciences.

Founded by the Brooklyn Institute of Arts and Sciences in 1890, the Biological Laboratory at Cold Spring Harbor, N.Y., was little more than a languishing outpost until the arrival of Charles B. Davenport in 1898. Over the course of two decades, the ambitious young biologist used his extraordinary administrative skills to transform the institution into the premier center of eugenical study and, as its director, to position himself as the leading spokesman for eugenical research in North America. The Davenport Papers (ca. 63 lin. feet) is a large and nearly comprehensive body of correspondence, lectures, diaries (1878-1942, mostly brief entries of an uneven character), student notebooks and family correspondence pertaining to Charles Davenport and the Cold Spring Harbor Laboratory. The collection is divided into two series, the Charles Davenport Papers, which provides valuable documentation of the development of American biology, animal and plant genetics, and eugenics during the period 1898-1942, with some perspective on the international eugenics movement. Series II, the Cold Spring Harbor Records (ca.20 lin. feet), consists largely of administrative correspondence relating to the laboratory, including Davenport's correspondence with Carnegie administrators (esp. Robert Woodward and John Merriam), accounts and reports concerning financial matters, publications, salaries, material relative to the early history of Cold Spring Harbor labs, and records relative to the numerous professional assistants who worked under Davenport. Among the major correspondents are the American Breeders Association, Committee on Eugenics; American Eugenics Society; American Society of Naturalists; Committee on a Study of the American Negro; Galton Society (see also the extensive correspondence with William K. Gregory); Eugenics Education Society (see Mrs. S. Gotto correspondence); International Congresses of Eugenics; International Federation of Eugenic Organizations, Committee on Race Crossing; National Committee on Mental Hygiene; National Committee on Prisons and Prison Labor; and the Pan-American Conference on Eugenics and Homiculture. There are correspondence and papers relating to the Station for Experimental Evolution, the Eugenics Record Office, and the Carnegie Institution of Washington, and a substantial series relating to a long-range study of children carried out at Letchworth Village, Thiles, New York. This note is currently under review for revision.

One of the seminal figures in the emergence of the Modern or Neo-Darwinian Synthesis during the mid-twentieth century, George Gaylord Simpson (1902-1984) helped define the unique contribution made by vertebrate paleontology to the life sciences. A specialist in Mesozoic and early Cenozoic mammals, Simpson's contributions to the fusion of Darwinian natural selection and Mendelian genetics were both empirical and theoretical, culminating in his major works Tempo and Mode in Evolution and The Meaning of Evolution. From his posts at the American Museum of Natural History (1927-1959), Columbia University (1945-1959), Harvard (1959-1967), and the University of Arizona (1967-1984), Simpson became one of the most influential paleontologists of the century, helped in part by his ability to write successfully for both a technical, professional audience and a popular audience. The Simpson Papers include a comprehensive assemblage of professional and personal correspondence, reflecting nealy all phases of Simpson's career. Written with charm, wit, and a sense of literary style, the correspondence touches on all aspects of modern paleontology, providing an important perspective on the emergence of contemporary evolutionary theory, biogeography, systematic theory and methodology, the relationship of science and religion, and creationism, as well as more general issues in scientific epistemology and social and political issues. The collection also includes autobiographical data and writings, lectures, class notes and papers, research data, material on his scientific expeditions (diaries in carbon form, photos, notes, etc.), publication material (he was author of some 800 publications), extensive photographic material, diplomas, and medals.